Question by Teppo: What are the advantages and disadvantages of taking Carim 100 mg?
I am intrigued specifically what are the benefits and drawbacks of having Modafinil 200 mg? Many thanks much.

Best answer:

Answer by Colin
Carim is just another name for modafinil… the only difference in yours is 100mg is half the dose of the 200mg tablets.

In the United States, modafinil is approved by the U.S. Food and Drug Administration only for the treatment of narcolepsy, obstructive sleep apnea/hypopnea and shift work sleep disorder. In some countries, it is also approved for idiopathic hypersomnia (all forms of excessive daytime sleepiness where causes can’t be established). The usual prescribed dosage for these disorders is 200 mg once a day (less commonly, 100 to 400 mg/day in one or two doses).

For conditions other than shift work sleep disorder, modafinil is normally taken in one dose in the morning or in two doses in the morning and at midday. It is generally not recommended to take modafinil after noon: modafinil is a relatively long-acting drug with a half-life of 15 hours, and taking it during the later part of the day carries a risk of sleep disturbances

Despite extensive research into the interaction of modafinil with a large number of neurotransmitter systems, a precise mechanism or set of mechanisms of action remains unclear. It seems that modafinil, like other stimulants, increases the release of monoamines, specifically the catecholamines norepinephrine and dopamine, from the synaptic terminals. However, modafinil also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a “wakefulness promoting agent” rather than a classic amphetamine-like stimulant. Despite modafinil’s histaminergic action, it still partially shares the actions of amphetamine-class stimulants due to its effects on norepinephrine and dopamine.

A National Institute on Alcohol Abuse and Alcoholism (NIAAA) study highlighted “the need for heightened awareness for potential abuse of and dependence on modafinil in vulnerable populations” due to the drug’s effect on dopamine in the brain’s reward center. However, the synergistic actions of modafinil on both catecholaminergic and histaminergic pathways lowers abuse potential as compared to traditional stimulant drugs while maintaining the effectiveness of the drug as a wakefulness promoting agent. Studies have suggested that modafinil “has limited potential for large-scale abuse” and “does not possess an addictive potential in naive individuals.”

Modafinil was shown to be an effective treatment for attention deficit hyperactivity disorder (ADHD),however in 2006 it was found by the FDA to be unfit for use by children for that purpose. It was rejected primarily due to one suspected case of Stevens-Johnson syndrome. Cephalon’s own label for Provigil now discourages its use by children for any purpose. Other potentially effective, but unapproved targets include the treatment of depression, bipolar depression,opiate & cocaine dependence,Parkinson’s disease, schizophrenia, and disease-related fatigue, as well as fatigue that is the side effect of another medication.

In most countries, here is a paper sheet with this sort of information with the tablets. If not, you really should discuss what you need to know with the pharmacist. Although pharmacists are sometimes called chemists, they are rather different and have specific traning in the areas.

Give your answer to this question below!

Question by Nic V: Is there a Hair Salon in Arizona that does Brazilian Hair Straightening?
I need a stylist that has been practicing this for at least 10 years. Does anybody know any in Arizona, there many in Florida are there any here? I don’t want to be part of someones learning process.

Best answer:

Answer by Sur La Mer
Yes, I’m sure of that, but I wouldn’t recommend them. There are many brands of hair straightening out there and they call them anyway they want to get your attention. Coco is another name brand. Some Japanese hair straightening processes can damage the hair and leave it flat and lifeless.
None is better than the other.
Ex. of one relaxer: http://monicabtheorganicstylist.wordpress.com/tag/hair-relaxers/

Keratin are not approved by the FDA. Visit their website & search for it in their web. If you’re thinking about the Brazilian treatment, there’s a danger about using formaldehyde, a chemical that causes cancer. The FDA does not restrict the use of that chemical in cosmetics.

A hairstylist in Portland, Or. is blowing a whistle on the treatment.
“A big red flag: About a month after she started using Brazilian Blowout on clients, Scrutton had the first nosebleed of her life.”
http://www.oregonlive.com/health/index.ssf/2010/10/
after_hair_stylist_becomes_sus.html
(Type it in if they moved the page. “After hairstylist becomes suspicious of Brazilian Blowout, tests find formaldehyde”.

Stylists and clients often wear gas masks or other protective equipment and still may feel the ill effects of this potentially fatal gas.

Many customers and stylists do not know that this Brazilian treatment often contains high concentrations of formaldehyde, a cancer-causing chemical.

Relaxers are for permanent, but they are damaging to hair.

Go to the FDA website & type in permanent or relaxers so you understand what are the side effects.
http://www.fda.gov/forconsumers/byaudien…

Here’s the newest news:
The Food and Drug Administration (FDA) recently seized tens of thousands of bottles of “Rio” hair relaxer products after determining they can cause severe hair loss or turn hair green.
http://blog.taragana.com/business/2010/0…

The FDA have warned consumers not to use “Rio Hair Naturalizer Systems,” a product imported from Brazil and sold through television infomercials by World Rio Corp. of Los Angeles.
http://www.fda.gov/Cosmetics/ProductandIngredientSafety/ProductInformation/ucm228898.htm

The official complaints against hair straightening products range from serious hair breakage and hair damage to serious scalp burns that may require an emergency room visit.
Example of what one suffering severe hair loss after Japanese Hair Straightening from YA HAIR:
I got my hair rebonded back in March and have lost more than a third of it since then. Everytime I run my hands through my hair, I lose 7-10 strands on average!
In the shower I lose clumps after shampooing and conditioning.
Bald spots are showing up in my hair.
I used to have beautiful thick hair, ho can I get it back?

Another ex: I used to have very curly, beautiful hair..and then i got it chemically straightened..DONT DO IT! when it started growing out, it was mess and even more difficult to work with than before. and once it was completely grown out, my hair was no longer curly..it is now this aweful wavy mess, and only certain spots are still curly.

Another example: I don’t recommend it. Hair went back to normal even before 4 months (it stated that the Keratin would stay on for 4months). Soft rebonding would be the better choice. I think the KeraStraight was a scam. Even the KeraStraight shampoo/conditioner did no contribution. It was a complete waste of money :/ However it was straight for awhile. But not very long.

Source(s):
I know hair. I have 4 decades of hair know-how. I have silky, shiny, soft, smooth very healthy hair down to my knees. Previously damaged by perming & dyeing in the 80’s & 90’s. I’ve known people in their 30’s whose hair stopped growing from ironing their hair in the 70’s.

Know better? Leave your own answer in the comments!